Actively Recruiting

All Genders
NCT07206095

Integrative Diagnosis for SCD and Other RADs

Led by Hospital Universitari Vall d'Hebron Research Institute · Updated on 2025-10-03

200

Participants Needed

9

Research Sites

389 weeks

Total Duration

On this page

Sponsors

H

Hospital Universitari Vall d'Hebron Research Institute

Lead Sponsor

H

Hospital Clinic of Barcelona

Collaborating Sponsor

AI-Summary

What this Trial Is About

INTEGRA aims at enabling personalized medicine for RHADs patients by the establishment of an integrative diagnostic approach based on deep phenotypic and genetic characterization through combining new generation methodologies.

CONDITIONS

Official Title

Integrative Diagnosis for SCD and Other RADs

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a confirmed or suspected diagnosis of hereditary rare hemolytic anemia such as sickle cell disease, thalassemia, congenital dyserythropoietic anemia, enzymopathy, unstable hemoglobin or altered oxygen affinity, hereditary stomatocytosis, hereditary pyropoikilocytosis, or hereditary spherocytosis with severe anemia (less than 8 g/dL) or inconclusive diagnosis
  • Patients with chronic hemolytic anemia and red cell smear compatible but inconclusive EMA binding test or genetic testing
  • Patients not undergoing stem cell transplantation or gene therapy at the time of inclusion
  • Patients with graft failure without a new transplant may be included
Not Eligible

You will not qualify if you...

  • Carrier traits in autosomal recessive hereditary anemias

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 9 locations

1

Hospital de la Santa Creu i Sant Pau

Barcelona, Barcelona, Spain, 08025

Actively Recruiting

2

Hospital Universitari Vall d'Hebron

Barcelona, Barcelona, Spain, 08035

Actively Recruiting

3

Hospital Sant Joan de Déu

Esplugues de Llobregat, Barcelona, Spain, 08950

Actively Recruiting

4

Hospital General de Granollers

Granollers, Barcelona, Spain, 08402

Actively Recruiting

5

Consorci Sanitari del Maresme - Hospital de Mataró

Mataró, Barcelona, Spain, 08304

Actively Recruiting

6

Parc Taulí Hospital Universitari

Sabadell, Barcelona, Spain, 08208

Actively Recruiting

7

Hospital Universitari Mútua de Terrassa

Terrassa, Barcelona, Spain, 08221

Actively Recruiting

8

Consorci Sanitari de Terrassa

Terrassa, Barcelona, Spain, 08227

Actively Recruiting

9

Hospital Universitari Arnau de Vilanova

Lleida, Lleida, Spain, 25198

Actively Recruiting

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Research Team

M

Mar Mañú Pereira PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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