Actively Recruiting
Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment
Led by Boston Medical Center · Updated on 2025-06-26
350
Participants Needed
1
Research Sites
279 weeks
Total Duration
On this page
Sponsors
B
Boston Medical Center
Lead Sponsor
N
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will identify unique signatures that people have which can cause pain by evaluating biological, psychological, and social markers using artificial intelligence. These markers can be used to accurately predict the response of diverse individuals with chronic low back pain (cLBP) to Mindfulness-Based Stress Reduction. This will help enhance clinician decision-making and the targeted treatment of chronic pain. The overall objective is to use a unique machine learning (ML) approach to determine the biomarker signature of persons undergoing mindfulness based stress reduction (MBSR) treatment for their chronic low back pain (cLBP). This signature will facilitate clinical prediction and monitoring of patient response to MBSR treatment. The design of the study is a single-arm clinical trial of the evidence-based MBSR program for patients with cLBP.
CONDITIONS
Official Title
Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chronic low back pain lasting at least 3 months with pain on at least half of the days in the past 6 months
- Willing and able to provide informed consent online or by telephone
- Speak English as the intervention manual is in English
You will not qualify if you...
- Recent worsening of pain in the past month, unexplained fever, or unexplained weight loss (red flags)
- Pregnancy
- Metastatic cancer
- Not a patient at a participating clinic or not planning to continue as a patient at a participating clinic for 6 or more months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Boston Medical Center
Boston, Massachusetts, United States, 02116
Actively Recruiting
Research Team
N
Natalia Morone, MD MS
CONTACT
J
Jose Baez, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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