Actively Recruiting

Phase Not Applicable
Age: 21Years - 60Years
All Genders
NCT06286202

Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial

Led by Singapore Institute of Technology · Updated on 2026-01-27

160

Participants Needed

5

Research Sites

173 weeks

Total Duration

On this page

Sponsors

S

Singapore Institute of Technology

Lead Sponsor

S

Singapore Anglican Community Services

Collaborating Sponsor

AI-Summary

What this Trial Is About

Adults with serious mental illnesses (such as schizophrenia and schizoaffective disorders) often experience a range of cognitive difficulties (such as memory, problem solving difficulties) that affect their ability to lead meaningful life roles. Cognitive remediation is an intervention to address cognitive difficulties in this group of mental health service users. Its implementation in less well-resourced community-based settings is less well-studied. Therefore, the aims of the study are: * To investigate the effects of cognitive remediation on various cognitive skills (such as attention, memory, problem-solving, facial expression recognition, taking others' perspectives etc), for participants with schizophrenia or schizoaffective disorders in community mental health settings. * To investigate if factors such as participants' motivation for engagement and social interaction can affect changes in cognitive skills and functional ability. Participants in the treatment group will attend computer-based cognitive exercises to improve their cognitive skills. They will also participate in group sessions facilitated by therapists to learn how to utilize strategies learned from the computer sessions in their daily lives. Participants in the control group will attend the usual rehabilitation activities in their respective community-based psychiatric rehabilitation centers. This research study will compare the differences in their cognitive performance, functional ability and recovery immediately after the intervention and 8 weeks later.

CONDITIONS

Official Title

Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial

Who Can Participate

Age: 21Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of schizophrenia or schizoaffective disorder according to DSM-V
  • Completed at least ten years of formal education with English as the main instructional language
  • Ability to speak and understand English to participate in the cognitive remediation program
Not Eligible

You will not qualify if you...

  • Known neurological diseases or epilepsy that affect cognitive remediation benefits
  • Inability to speak and understand English
  • Hospitalized within the past one month
  • Global Assessment of Functioning score of 30 or below indicating very low functioning

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 5 locations

1

Anglican Care Center-Bukit Batok

Singapore, Singapore

Actively Recruiting

2

Anglican Care Center-Hougang

Singapore, Singapore

Actively Recruiting

3

Anglican Care Center-Pasir Ris

Singapore, Singapore

Not Yet Recruiting

4

Anglican Care Center-Simei

Singapore, Singapore

Actively Recruiting

5

Anglican Care Center-Yishun

Singapore, Singapore

Not Yet Recruiting

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Research Team

B

Bhing-Leet Tan, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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