Actively Recruiting

Phase Not Applicable
Age: 12Years - 18Years
All Genders
NCT06691867

Integrative Training Program for Pediatric Sickle Cell Pain

Led by Emory University · Updated on 2025-11-14

155

Participants Needed

4

Research Sites

133 weeks

Total Duration

On this page

Sponsors

E

Emory University

Lead Sponsor

N

National Center for Complementary and Integrative Health (NCCIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to answer the question: does a group training program specifically for teens with chronic sickle cell disease (SCD) pain that teaches skills to strengthen the mind and body help improve everyday functioning and reduce pain symptoms? The program will be tailored to address challenges related to frequent or chronic sickle cell pain and may improve participants' physical and emotional health. The program, called I-STRONG for SCD (Integrative Strong Body and Mind Training for Sickle Cell Disease), may help improve everyday functioning and pain symptoms in teens with chronic pain related to SCD. The research team aims to determine how participants (teens and parents) respond to this program.

CONDITIONS

Official Title

Integrative Training Program for Pediatric Sickle Cell Pain

Who Can Participate

Age: 12Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent form for adolescents 18 years old and their caregivers
  • For children under 18, informed assent and parental consent to participate
  • Willingness to follow all study procedures and be available for the study duration
  • Male or female adolescents aged 12 to 18 years; no age limits for caregivers
  • Documented diagnosis of sickle cell disease of any type for adolescents
  • Adolescent scores at least 3 on the Pediatric Pain Screening Tool
  • Adolescent reports typical pain intensity of at least 4 on a 0-10 scale in the past week
  • Adolescent on stable disease-modifying treatments without recent changes in dosage for the past 3 months
  • Ability to speak and read English
Not Eligible

You will not qualify if you...

  • Adolescents with other medical conditions causing pain unrelated to sickle cell disease
  • Adolescents who have had genetic or hematopoietic stem cell therapy
  • Any physical or psychological condition that prevents participation
  • Adolescents currently receiving active nonpharmacological treatments like behavioral pain management, physical therapy, or acupuncture that overlap with the study

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 4 locations

1

Connecticut Children's Medical Center

Hartford, Connecticut, United States, 06106

Actively Recruiting

2

Children's Healthcare of Atlanta

Atlanta, Georgia, United States, 30322

Actively Recruiting

3

Arthur M. Blank Hospital | Children's Healthcare of Atlanta

Atlanta, Georgia, United States, 30329

Actively Recruiting

4

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States, 45229

Actively Recruiting

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Research Team

S

Soumitri Sil, PhD, ABPP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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