Actively Recruiting
Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study
Led by Northwestern University · Updated on 2026-04-08
500
Participants Needed
6
Research Sites
186 weeks
Total Duration
On this page
Sponsors
N
Northwestern University
Lead Sponsor
E
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Two combination interventions (HIV Case Finding Intervention and HIV Treatment Intervention), each with mHealth and Peer Navigation components, will be evaluated in two 48-week parallel hybrid effectiveness/implementation trials among youth aged 15-24 in Nigeria.
CONDITIONS
Official Title
Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 15 to 24 years
- Male birth sex of any current gender identity (for HIV Case Finding Intervention)
- Understand basic English, Yoruba, Hausa, Igbo, or Pidgin English
- For PrEP component, must be HIV-negative
- HIV seropositive (for HIV Treatment Intervention)
- Initiating ART for the first time at a Clinical Research Performance Site (CRPS) clinic or satellite clinic
- Intention to remain a CRPS patient during follow-up
You will not qualify if you...
- Unable to provide consent
- No parental permission if aged 15 and not emancipated
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 6 locations
1
University of Uyo Teaching Hospital
Uyo, Akwa Ibom State, Nigeria
Actively Recruiting
2
Federal Medical Center
Makurdi, Benue State, Nigeria
Actively Recruiting
3
Taraba State Specialist Hospital
Jalingo, Taraba State, Nigeria
Actively Recruiting
4
University of Nigeria Teaching Hospital
Enugu, Nigeria
Actively Recruiting
5
Aminu Kano Teaching Hospital
Kano, Nigeria
Actively Recruiting
6
Lagos University Teaching Hospital
Lagos, Nigeria
Actively Recruiting
Research Team
R
Robert Garofalo, MD
CONTACT
L
Lisa M Kuhns, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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