Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT07209930

Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial

Led by University College Dublin · Updated on 2025-10-07

24

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

Sponsors

U

University College Dublin

Lead Sponsor

T

Taighde Éireann - Research Ireland

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to investigate if blood glucose responses are similar between and within individuals in response to standardized exercise in adults with and without Type 1 diabetes. The main questions it aims to answer are: What is the reproducibility of acute glycaemic responses to exercise within and between subjects in adults living with Type 1 Diabetes and in healthy adults? What is the agreement between glucose levels obtained by continuous glucose monitor (CGM) and blood glucose monitor? Participants will cycle on a cycle ergometer or rest after consuming a standardized breakfast, while glucose levels are monitored by CGM and capillary blood sampling.

CONDITIONS

Official Title

Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 60 years old
  • Healthy individuals
  • Engage in physical activity at least once a week
  • For Type 1 diabetes phase: diagnosed with Type 1 diabetes for more than 18 months
  • For Type 1 diabetes phase: have awareness of hypoglycemia symptoms
Not Eligible

You will not qualify if you...

  • Presence of cardiovascular disease or contraindications to exercise
  • Infectious or inflammatory conditions
  • Chronic kidney or liver disease
  • Pregnancy
  • Gestational diabetes
  • Diagnosed eating disorders
  • Any physical or mental condition preventing participation
  • For healthy phase: diagnosis of diabetes mellitus (type 1 or type 2)
  • For Type 1 diabetes phase: inability to self-manage diabetes

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

University College Dublin

Dublin, Dublin, Ireland, D04 V1W8

Actively Recruiting

Loading map...

Research Team

V

Veronica Merlo

CONTACT

K

Katy Horner

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

OTHER

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial | DecenTrialz