Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04942080

Interest of CALR Allele Burden in Diagnosis and Follow-up of Patients With CALR Mutated Myeloproliferative Syndromes (CALRSUIVI)

Led by University Hospital, Angers · Updated on 2026-03-06

260

Participants Needed

10

Research Sites

443 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Angers

Lead Sponsor

L

Ligue contre le cancer, France

Collaborating Sponsor

AI-Summary

What this Trial Is About

Prospective study to evaluate the relevance of CALR allele burden monitoring as a molecular marker of disease progression.

CONDITIONS

Official Title

Interest of CALR Allele Burden in Diagnosis and Follow-up of Patients With CALR Mutated Myeloproliferative Syndromes (CALRSUIVI)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • Affiliated to the national social security system
  • Diagnosed with CALR mutated myeloproliferative neoplasm between 2006 and 2020
  • Have at least one available sample at diagnosis or before cytoreductive treatment
  • Signed consent to participate in the study
  • Included or consenting to be included in the national clinical-biological database of France Intergroupe Syndrome Myéloprolifératifs (FIM)
Not Eligible

You will not qualify if you...

  • Have another active hematological disease or cancer at time of diagnosis
  • Subject to a legal protection scheme or unable to give consent

AI-Screening

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Trial Site Locations

Total: 10 locations

1

CHU Angers

Angers, France

Actively Recruiting

2

Chu Bordeaux

Bordeaux, France, 33604

Actively Recruiting

3

Chu Brest

Brest, France, 29200

Actively Recruiting

4

Ch Cholet

Cholet, France, 49300

Actively Recruiting

5

Ch Le Mans

Le Mans, France, 72037

Actively Recruiting

6

Ch Morlaix

Morlaix, France, 29672

Actively Recruiting

7

AP-HP Henri Mondor

Paris, France, 94010

Actively Recruiting

8

Chu Poitiers

Poitiers, France, 86021

Actively Recruiting

9

Ch Quimper

Quimper, France, 29107

Actively Recruiting

10

Chu Tours

Tours, France, 37000

Actively Recruiting

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Research Team

L

Laurane COTTIN, Doctor

CONTACT

E

Emma BLANCHET

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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