Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
ID06647849

Interest of Simulation Training on the Announcement of Early Pregnancy Loss on the Psychological Impact of the Patients

Led by University Hospital, Angers · Updated on 2025-11-18

1000

Participants Needed

28

Research Sites

56 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Angers

Lead Sponsor

D

Direction Générale de l'Offre de Soins

Collaborating Sponsor

AI-Summary

What this Trial Is About

Early pregnancy loss, or spontaneous miscarriage, is defined as the loss of a pregnancy before 14 weeks of amenorrhea and occurs in about 10 to 15% of pregnancies, with higher risks as maternal age increases. This research investigates how specific simulation training for interns on announcing early pregnancy loss affects the psychological experience of women following miscarriage, addressing the emotional impact and potential long-term effects such as psychological distress and fertility concerns. The study is a randomized, single-blind, multicenter trial conducted by the University Hospital, Angers. Participants are assigned to one of two groups: the "with training" group includes centers where interns receive specialized simulation training on delivering miscarriage news, conducted by a team of an obstetrician-gynecologist and a psychologist within the maternity ward. The "untrained" group centers follow standard care where interns do not receive this specific training. Interns in the untrained group will be offered training after the study period. The training aims to improve communication skills and patient experience during the announcement of early spontaneous miscarriage. Women enrolled in the study are evaluated over time with psychological assessments including the Perinatal Grief Scale at 3, 6, and 12 months post-miscarriage, and the Impact of Event Scale-Revised at 1 and 18 months. Additional evaluations include patients' feelings about how the miscarriage announcement was made, and fertility outcomes such as time to new pregnancy and pregnancy rates beyond 14 weeks. The study measures how simulated training may influence these outcomes, with follow-up visits and questionnaires conducted to monitor the psychological impact and fertility status.

CONDITIONS

Brief Title

Interest of Simulation Training on the Announcement of Early Pregnancy Loss on the Psychological Impact of the Patients

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patient
  • Presenting to gynecological emergency department
  • Diagnosed with terminated pregnancy or spontaneous miscarriage before 14 weeks' amenorrhea
  • Miscarriage announced by an intern
  • Affiliated to or benefiting from social security
  • Signed informed consent form
Not Eligible

You will not qualify if you...

  • Unwanted pregnancy
  • Spontaneous hemorrhagic miscarriage requiring surgical management
  • Ectopic pregnancy
  • Miscarriage from assisted reproduction treatment
  • History of 3 or more miscarriages
  • Poor understanding of French language
  • Person deprived of liberty by judicial or administrative decision
  • Person under forced psychiatric care
  • Person under legal protection measure
  • Unable to give consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - At time of diagnosis and announcement

Participants receive miscarriage announcement by interns who either have simulation training in early miscarriage announcement or standard care without specific training.

1 visit (in-person) at the emergency department

Follow-up

Duration - Up to 18 months post-miscarriage

Participants' psychological experience and fertility outcomes are assessed at multiple time points after miscarriage announcement.

Assessments at 1 month, 3 months, 6 months, 12 months, and 18 months

Trial Site Locations

Total: 28 locations

1

University Hospital of Amiens

Amiens, France

Actively Recruiting

2

University Hospital of Angers

Angers, France

Actively Recruiting

3

University Hospital of Bordeaux

Bordeaux, France

Not Yet Recruiting

4

University Hospital of Brest

Brest, France

Not Yet Recruiting

5

Femme Mere Enfant Hospital

Bron, France

Not Yet Recruiting

6

University Hospital of Caen

Caen, France

Actively Recruiting

7

CH Chalon-sur-Saône

Chalon-sur-Saône, France

Actively Recruiting

8

CH Cholet

Cholet, France

Actively Recruiting

9

University Hospital of Clermont-Ferrand

Clermont-Ferrand, France

Actively Recruiting

10

University Hospital of Dijon

Dijon, France

Actively Recruiting

11

CHU Grenoble

Grenoble, France

Actively Recruiting

12

Vendée Departmental Hospital center

La Roche-sur-Yon, France

Actively Recruiting

13

Le Mans Hospital

Le Mans, France

Actively Recruiting

14

Jeanne de Flandre Hospital

Lille, France

Actively Recruiting

15

University Hospital of Limoges

Limoges, France

Actively Recruiting

16

Hopital Nord (Marseille Public University Hospital System)

Marseille, France

Actively Recruiting

17

La Conception Hospital (Marseille Public University Hospital System)

Marseille, France

Actively Recruiting

18

University Hospital of Montpellier

Montpellier, France

Actively Recruiting

19

University Hospital of Nancy

Nancy, France

Actively Recruiting

20

University Hospital of Nantes

Nantes, France

Actively Recruiting

21

CHU Nice

Nice, France

Actively Recruiting

22

University Hospital of Nimes

Nîmes, France

Actively Recruiting

23

CHU Orléans

Orléans, France

Actively Recruiting

24

Poissy intercommunal hospital center

Poissy, France

Actively Recruiting

25

University Hsopital of Reims

Reims, France

Actively Recruiting

26

University Hospital of Rennes

Rennes, France

Actively Recruiting

27

University Hospital of Rouen

Rouen, France

Actively Recruiting

28

University Hospital of Saint Etienne

Saint-Etienne, France

Actively Recruiting

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Research Team

G

Guillaume Lengendre, MD, PhD

D

DRI UH Angers

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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