Actively Recruiting

Phase 3
Age: 18Years - 75Years
FEMALE
Healthy Volunteers
NCT06559696

Internal Mammary Lymph Nodes Irradiation in High-risk Breast Cancer After Neoadjuvant Chemotherapy

Led by Fujian Medical University Union Hospital · Updated on 2024-09-19

722

Participants Needed

1

Research Sites

417 weeks

Total Duration

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AI-Summary

What this Trial Is About

The aim of this study is to explore the impact of internal mammary nodal irradiation on disease-free survival in high-risk breast cancer patients (ypN+or supra/subclavicular lymph node positive) after neoadjuvant chemotherapy.

CONDITIONS

Official Title

Internal Mammary Lymph Nodes Irradiation in High-risk Breast Cancer After Neoadjuvant Chemotherapy

Who Can Participate

Age: 18Years - 75Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically confirmed invasive breast cancer
  • Underwent neoadjuvant chemotherapy
  • Eastern Cooperative Oncology Group Performance Status Scale 0-2
  • ypN+ after neoadjuvant chemotherapy or supraclavicular/subclavicular lymph node metastasis before system therapy
  • No distant metastases
  • No internal mammary nodes metastases based on images before system therapy
  • Willing to follow up
  • Written,informed consent
Not Eligible

You will not qualify if you...

  • Without neoadjuvant chemotherapy
  • Distant metastases
  • Simultaneous bilateral breast cancer
  • Pathological confirmation or imaging consideration of lymph node metastasis in the internal mammary before system therapy
  • Had simultaneous or previous secondary malignancies, except for non-malignant melanoma skin cancer, papillary thyroid / follicular carcinoma, cervical carcinoma in situ, contralateral non-invasive breast cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fujian Medical University Union Hospital

Fuzhou, Fujian, China, 350001

Actively Recruiting

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Research Team

Y

Yong Yang, M.S

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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