Actively Recruiting
International CIPN Assessment and Validation Study
Led by University of Milano Bicocca · Updated on 2025-07-25
1000
Participants Needed
30
Research Sites
290 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is an observational study of chemotherapy-induced peripheral neurotoxicity (CIPN) patients to be investigated prospectively in order to assess responsiveness of a set of outcome measures in an international multi-center study.
CONDITIONS
Official Title
International CIPN Assessment and Validation Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Candidates for neurotoxic chemotherapy at doses expected to cause nerve damage
- Male or female aged 18 years or older
- Able to provide signed informed consent
- Willing to complete all study activities and follow-up visits
- Karnofsky performance score of 70 or higher
You will not qualify if you...
- Poor prognosis making completion of chemotherapy unlikely
- Neurologic conditions interfering with assessments (e.g., brain tumor, metastases)
- Severe depression complicating assessments
- Chronic use of antiepileptic drugs, antidepressants, or major analgesics unless stable for 3 months
- Use of preventive interventions like antioxidants or cryotherapy
- Current use of medications known to cause peripheral nerve toxicity besides chemotherapy
- Any other condition reducing ability to provide satisfactory data
- Previous treatment with neurotoxic chemotherapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 30 locations
1
Birmingham School of Nursing, University of Alabama
Birmingham, Alabama, United States, 35294
Not Yet Recruiting
2
Northside Hospital
Atlanta, Georgia, United States, 30342
Not Yet Recruiting
3
JHU
Baltimore, Maryland, United States, 21224
Not Yet Recruiting
4
University of Michigan School of Nursing
Ann Arbor, Michigan, United States, 48109
Not Yet Recruiting
5
Columbia University Irving Medical Center
New York, New York, United States, 10027
Not Yet Recruiting
6
Cancer Center/Wexner Medical Center - Ohio State Medical Oncology Division
Columbus, Ohio, United States, 43220
Not Yet Recruiting
7
Dartmouth-Hitchcock Medical Center
Lebanon, Pennsylvania, United States, 03756
Not Yet Recruiting
8
University of Vermont Medical Center
Burlington, Vermont, United States, 05445
Not Yet Recruiting
9
Brain and Mind Center
Sydney, Australia
Not Yet Recruiting
10
Dept. of Neurology, Medical University of Vienna
Vienna, Austria
Not Yet Recruiting
11
International Centre for Diarrhoeal Disease Research
Dhaka, Bangladesh
Not Yet Recruiting
12
Clínica AMO
Salvador, Brazil
Not Yet Recruiting
13
The Ottawa Hospital
Ottawa, Canada
Not Yet Recruiting
14
Aarhus University Hospital
Aarhus, Denmark
Withdrawn
15
Hôpital Percy
Clamart, France
Not Yet Recruiting
16
CHU Dupuytren
Limoges, France
Not Yet Recruiting
17
Center for Molecular Medicine
Cologne, Germany
Not Yet Recruiting
18
University of Larissa
Larissa, Greece
Not Yet Recruiting
19
"Saint Andrew's" State General Hospital
Pátrai, Greece
Actively Recruiting
20
San Gerardo Hospital
Monza, Mb, Italy, 20900
Actively Recruiting
21
Ospedale Valduce
Como, Italy, 22063
Withdrawn
22
Ospedale Policlinico San Martino
Genova, Italy
Actively Recruiting
23
A.O.U. Policlinico "G. Martino"
Messina, Italy
Not Yet Recruiting
24
Padova Hospital
Padova, Italy
Not Yet Recruiting
25
Azienda Ospedaliera Universitaria
Verona, Italy
Not Yet Recruiting
26
Medical Oncoloy Unit - University of Nairobi
Nairobi, Kenya
Not Yet Recruiting
27
Centro Hospitalar Vila Nova de Gaia/Espinho
Vila Nova de Gaia, Portugal
Not Yet Recruiting
28
Dong-A University - Internal Medicine Dept.
Busan, South Korea
Actively Recruiting
29
Hospital Universitari de Bellvitge-ICO L'Hospitalet
Barcelona, Spain
Actively Recruiting
30
University of Basel - Department of Sport, Exercise and Health
Basel, Switzerland
Not Yet Recruiting
Research Team
G
GUIDO CAVALETTI, MD
CONTACT
P
PAOLA ALBERTI, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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