Head and thorax elevation during cardiopulmonary resuscitation using circulatory adjuncts is associated with improved survival.
Johanna C Moore, Paul E Pepe, Kenneth A Scheppke...
https://pubmed.ncbi.nlm.nih.gov/35933057Actively Recruiting
Age: 18Years +
All Genders
ID05588024
International Device Assisted Controlled Sequential Elevation CPR Registry
Led by Hennepin Healthcare Research Institute · Updated on 2025-06-12
5000
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research tracks the use and outcomes of a specialized approach to cardiac arrest care in emergency medical systems across the US and Europe. It focuses on patients who receive a combination of devices and techniques including a Head Up CPR positioning device, an impedance threshold device (ITD), and either manual active compression-decompression CPR or automated compression CPR. The registry aims to understand how this system of care is applied rapidly during cardiac arrest and its effects on patient outcomes. All patients in this observational registry receive the Head Up CPR based bundle of care, which includes multiple FDA-approved devices: manual or automated CPR methods combined with an ITD and an automated device that elevates the head and thorax in a controlled way. Emergency medical systems using these protocols submit de-identified data about their cardiac arrest cases, both before and after adopting the Head Up CPR bundle. Participants are monitored during cardiac arrest with continuous measurements such as end tidal CO2 and cerebral oximetry if available. Researchers collect data on return of spontaneous circulation, survival up to 60 days, and neurological function outcomes. The registry securely stores all patient data to study the effects of this device-assisted CPR method over time.
CONDITIONS
Brief Title
International Device Assisted Controlled Sequential Elevation CPR Registry
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Patient is at least 18 years of age
- Patient is in active cardiac arrest defined by ventricular fibrillation, ventricular tachycardia, pulseless electrical activity, or asystole at enrollment
- Patient receives either active-compression decompression CPR, automated suction-cup based CPR with an impedance threshold device, or manual CPR with an impedance threshold device
- Patient receives device assisted controlled elevation of the head and thorax during CPR
You will not qualify if you...
- Prisoners
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Implementation
Duration - Up to around 40 minutes during cardiac arrest
Participants undergo CPR using a Head Up CPR based bundle of care, which includes device assisted controlled elevation of the head and thorax along with CPR methods and an impedance threshold device.
1 emergency treatment episode
Long-term Monitoring
Duration - Up to 60 days
Participants are observed for survival and neurological function outcomes after the CPR intervention.
Trial Site Locations
Total: 1 location
1
Hennepin Healthcare Research Institute
Minneapolis, Minnesota, United States, 55415
Actively Recruiting
Loading map...
Research Team
J
Johanna C Moore, MD, MS
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Survival for Nonshockable Cardiac Arrests Treated With Noninvasive Circulatory Adjuncts and Head/Thorax Elevation.
Kerry M Bachista, Johanna C Moore, José Labarère...
https://pubmed.ncbi.nlm.nih.gov/38240504Faster time to automated elevation of the head and thorax during cardiopulmonary resuscitation increases the probability of return of spontaneous circulation.
Johanna C Moore, Sue Duval, Charles Lick...
https://pubmed.ncbi.nlm.nih.gov/34793874