Actively Recruiting
International Pediatric Adrenocortical Tumor Registry
Led by St. Jude Children's Research Hospital · Updated on 2025-12-18
9999
Participants Needed
5
Research Sites
2043 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to collect demographic and medical information including detailed family history of cancer of children and adolescents with adrenocortical tumors in order to learn more about the clinical and epidemiological aspects, treatment modalities, and outcome of patients with this rare disease, worldwide. In addition, investigators at St. Jude Children's Research Hospital (SJCRH) plan to perform molecular studies of tumor cells aimed to clarify the role of the TP53 gene and other genetic pathways in these tumors. They aim to obtain relevant biological material from participants with adrenocortical tumor (ACT), their biological parents, and relatives for determination of the TP53 germline status, molecular studies of the TP53 gene, and other molecular pathways.
CONDITIONS
Official Title
International Pediatric Adrenocortical Tumor Registry
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participant suspected or confirmed to have an adrenocortical tumor (adenoma, carcinoma, or undefined histology)
- Participant is 21 years old or younger at diagnosis
- Signed informed consent for participation
- Relative of a participant with ACT and TP53 mutation who has a diagnosis of malignant tumor
- Biological parent of a participant with ACT
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Stanford University
Stanford, California, United States, 94305
Completed
2
All Children's Hospital/St. Petersburg Hospital
St. Petersburg, Florida, United States, 33701
Completed
3
The Children's Medical Center
Dayton, Ohio, United States, 45404
Actively Recruiting
4
St. Jude Children's Research Hospital
Memphis, Tennessee, United States, 38105
Actively Recruiting
5
Cook Children's Medical Center
Fort Worth, Texas, United States, 76104
Completed
Research Team
R
Raul C Ribeiro, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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