Actively Recruiting
International Surveillance of Antimicrobial Resistance in Cirrhosis-Related Infections
Led by Hospital Italiano de Buenos Aires · Updated on 2024-10-10
1000
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to monitor antibiotic resistance patterns in patients with cirrhosis who develop bacterial infections. Cirrhosis causes severe liver scarring, putting patients at high risk for serious infections that are often life-threatening. Since bacterial resistance is increasing, especially in Latin America where local guidelines are lacking, this study seeks to create a surveillance system specific to the region to improve antibiotic use and patient care. The study collects data from hospitals across Latin America to track bacterial infections and their resistance to antibiotics such as ceftriaxone, vancomycin, and carbapenems. It focuses on infections confirmed by culture either at hospital admission or during the stay. The program generates periodic reports on resistance patterns to help guide doctors in choosing effective antibiotics for cirrhosis patients based on real-time regional data. Participants will have their bacterial infections monitored through culture tests, and data will be gathered continuously to observe resistance trends. Researchers will measure the proportion of multidrug-resistant, extensively drug-resistant, and pan drug-resistant organisms within one week. The study also tracks susceptibility to various antibiotics and combinations. This ongoing surveillance aims to develop region-specific treatment guidelines and improve outcomes for patients with cirrhosis and bacterial infections over the long term.
CONDITIONS
Brief Title
International Surveillance of Antimicrobial Resistance in Cirrhosis-Related Infections
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Episodes of culture-confirmed bacterial infections
- Patients diagnosed with cirrhosis
- Infections diagnosed either at the time of hospital admission or during hospitalization
You will not qualify if you...
- History of solid organ or hematopoietic stem cell transplantation
- Declined to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Ongoing throughout hospitalization and infection episodes
Participants who have bacterial infections related to cirrhosis are observed to monitor antibiotic resistance patterns.
Visits occur as needed during hospital stay depending on infection episodes
Trial Site Locations
Total: 1 location
1
Hospital Italiano de Buenos Aires
Buenos Aires, Buenos Aires F.D., Argentina, C1199ABB.
Actively Recruiting
Research Team
S
Sebastián M Marciano, Principal Investigator.
G
Gonzalo Gomez Perdiguero, Registry coordinator
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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