Online Psychological Treatment Study for Adult Cancer Survivors with Anxiety or Depression Assessing Different Therapy Components Over 10 Weeks

What this Trial Is About

Researchers are evaluating internet-delivered psychological treatments for cancer survivors who have ongoing psychiatric symptoms such as anxiety or depression. This trial aims to identify which specific therapy components contribute most to improving the negative psychological long-term effects of cancer. The study is a randomized factorial trial enrolling 400 cancer survivors with clinically significant psychiatric symptoms. Participants receive variations of a 10-week therapist-guided online treatment combining support and information with behavioral activation, systematic exposure with mindfulness training, and promotion of health behaviors like exercise, diet, and sleep improvement. There are eight different treatment groups, each including different combinations of these components, to assess their individual and combined effects. During the study, participants complete weekly assessments before, during, and after treatment, including measures of general anxiety, depressive symptoms, and fear of cancer recurrence. Additional evaluations cover health anxiety, somatic symptoms, body image distress, disability, treatment satisfaction, and adverse effects. Follow-up assessments continue up to 12 months post-treatment. Participants access the program via electronic devices and must have sufficient Swedish language skills to engage with the text-based online platform.

Internet-Delivered Psychological Treatment for Cancer Survivors