Actively Recruiting
Internet-Delivered Psychological Treatment for Cancer Survivors
Led by Karolinska Institutet · Updated on 2025-11-21
400
Participants Needed
1
Research Sites
350 weeks
Total Duration
On this page
Sponsors
K
Karolinska Institutet
Lead Sponsor
R
Region Stockholm
Collaborating Sponsor
AI-Summary
What this Trial Is About
Negative psychological effects of cancer are common, but cancer survivors are rarely offered structured psychological treatment. Internet-delivered treatments have shown some promise, but specific treatment components have not been empirically evaluated which means that it is not clear which therapies that should be prioritized. In this randomized factorial trial at Karolinska Institutet, Stockholm, Sweden, 400 cancer survivors with psychiatric symptoms are enrolled in variations on a 10-week therapist-guided online psychological treatment intended to address the negative psychological long-term effects of cancer. The aim is to determine the contribution of treatment components to the overall effect.
CONDITIONS
Official Title
Internet-Delivered Psychological Treatment for Cancer Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Cancer survivor at least 0.5 years after main therapy
- Clinically significant anxiety or depression (Patient Health Questionnaire 9 [PHQ-9]≥10, or Generalized Anxiety Disorder 7 [GAD-7]≥8, or 9-item Fear of Cancer Recurrence Inventory [FCRI-9]≥16)
- At least 18 years old
- Resident of Region Stockholms, Västra Götalandsregionen, or Region Skåne, Sweden (listed and de facto)
- Sufficient technical knowledge and knowledge of the Swedish language to take part in a text-based online treatment
- Continuous access to an electronic device that can be used to access the study web platform
You will not qualify if you...
- Recurrent thoughts of suicide, as based on clinical judgement aided by the structured interview and MADRS-S item 9
- Severe medical condition (e.g., very poor prognosis, stage IV cancer), severe psychiatric disorder (e.g., psychotic disorder, bipolar disorder, severe substance use disorder, severe depression), or medical treatment (e.g., chemotherapy, immunotherapy, radiotherapy) that makes the treatment unfeasible
- Other ongoing psychological treatment
- Continuous psychotropic medication not stable for the past 4 weeks, or not expected to remain stable during the treatment period
- Planned absence for more than one week of the intended treatment period
- No completion of the pre-treatment assessment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Karolinska Institutet
Stockholm, Sweden
Actively Recruiting
Research Team
E
Erland Axelsson, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
TREATMENT
Number of Arms
8
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here