Actively Recruiting
Interstitial Lung Disease and Obstructive Sleep Apnea
Led by Dan Liu · Updated on 2026-02-10
70
Participants Needed
1
Research Sites
382 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Clinically, all patients with interstitial lung disease(ILD) were observed, and relevant clinical data were collected. Bronchoscopic specimens were collected according to the condition of the enrolled patients, and the rapid on site evaluation(ROSE) was evaluated, combined with the metagenomic next generation sequencing(mNGS) results of these patients. To observe the etiology and biological characteristics of exacerbation in patients with interstitial lung disease. All patients undergo polysomnography (PSG) and drug-induced sleep endoscopy(DISE). The biological specimens was obtained for molecular biology or other tests.We detected ZNF331, Claudin1, Claudin2, Claudin3, Claudin4, and IL22 as biomarkers to differentiate the diagnostic efficiency of OSA in ILD, ILD+OSA, OSA, and Ctrl groups, respectively
CONDITIONS
Official Title
Interstitial Lung Disease and Obstructive Sleep Apnea
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over 18 years old and under 80 years old
- Clinical diagnosis of interstitial lung disease or obstructive respiratory sleep apnea syndrome
- Patient is conscious and capable of signing informed consent
- Patient can wear a polysomnograph for monitoring
You will not qualify if you...
- Malignant tumors
- Severe heart failure
- Uremia
- Autoimmune diseases
- Pulmonary embolism and end-stage chronic obstructive pulmonary disease
- Mental illness that prevents signing informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tianjin Medical University General Hospital
Tianjin, China, 300000
Actively Recruiting
Research Team
D
Dan Liu
CONTACT
J
Jing Feng
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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