Actively Recruiting
Interstitial Lung Disease Trajectories in Patients With Systemic Sclerosis
Led by Central Hospital, Nancy, France · Updated on 2024-08-27
600
Participants Needed
1
Research Sites
122 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Systemic sclerosis (SSc) is a heterogeneous systemic autoimmune disease with distinct prognosis according to patients. In patients with systemic sclerosis, interstitial lung disease (ILD) concerns almost 50 % of patients and represents the main cause of mortality. Disease course in SSc-ILD is highly variable: patients can experience stable disease, slow or fast progression. Prevention of ILD progression now represents a key objective of SSc-ILD management. The understanding of the course and patterns of SSc-ILD progression is necessary, as reliable prediction tools that allow the stratification of the risk of progression. We aimed to identify the longitudinal trajectories of ILD in SSc patients using latent class mixed models and to examine their associations with SSc characteristics.
CONDITIONS
Official Title
Interstitial Lung Disease Trajectories in Patients With Systemic Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with systemic sclerosis according to 2013 ACR/EULAR criteria
- Patients with interstitial lung disease on HRCT chest
- Patients with PFT at ILD diagnosis and at least 1 PFT evaluation during follow-up
You will not qualify if you...
- Patients with an alternative diagnosis of SSc-associated ILD such as silicosis, sarcoidosis, lung cancer, or other significant lung abnormalities
AI-Screening
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Trial Site Locations
Total: 1 location
1
CHU Nancy
Vandœuvre-lès-Nancy, Grand Est, France, 54500
Actively Recruiting
Research Team
P
Paul DECKER, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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