Actively Recruiting
Intervention for Communication Quality of Life in Primary Progressive Aphasia
Led by Maya Henry · Updated on 2026-04-21
30
Participants Needed
1
Research Sites
69 weeks
Total Duration
On this page
Sponsors
M
Maya Henry
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn whether a personalized, multi-component, virtual speech language treatment program can improve communication and quality of life for adults with primary progressive aphasia (PPA) and their primary communication partners. The study will enroll participants who speak English and/or Spanish. The main questions the study aims to answer are: * Is the telerehabilitation program feasible and acceptable for people with PPA and their study partners? * Do participants with PPA and study partners find treatment beneficial? * What patterns of treatment response are seen in participants? * Which outcome measures are most useful for evaluating changes in communication and quality of life? Researchers will compare participants who receive intervention immediately to participants assigned to a waitlist control group (who will receive treatment after a delay) to see whether participation in the treatment program is associated with improvements in communication and quality of life. Participants will: * Take part in speech language therapy sessions delivered by video visit that combine restorative, compensatory, and partner-focused communication strategies. Treatment may take place after a waiting period. * Receive education and communication training together with their partner. * Complete speech, language, and cognitive assessments. * Complete questionnaires about communication abilities, daily functioning, and quality of life.
CONDITIONS
Official Title
Intervention for Communication Quality of Life in Primary Progressive Aphasia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of primary progressive aphasia (PPA) or "PPA-plus"
- MMSE score of 15 or higher
- Ability to produce single monosyllabic words intelligibly
- Speak English, Spanish, or both (bilingual speakers)
- Hearing and vision adequate for teleconference participation
- Availability of a study partner who can attend teleconference sessions
- Study partner willing to participate in assessments and treatment sessions
- Study partner speaks English, Spanish, or both
- Study partner's hearing and vision adequate for teleconference participation
- Participant and/or study partner have basic computer experience
You will not qualify if you...
- Other central nervous system or medical diagnoses that explain symptoms
- Psychiatric diagnoses that explain symptoms
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Texas
Austin, Texas, United States, 78712
Actively Recruiting
Research Team
H
Henry Lab Research Coordinator
CONTACT
G
Grasso Lab Research Coordinator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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