Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
NCT06458075

Intervention to Improve Communication and Medication Adherence in Lupus

Led by Duke University · Updated on 2025-09-30

480

Participants Needed

1

Research Sites

230 weeks

Total Duration

On this page

Sponsors

D

Duke University

Lead Sponsor

N

National Institute on Minority Health and Health Disparities (NIMHD)

Collaborating Sponsor

AI-Summary

What this Trial Is About

CO-LEAD is an intervention to improve patient-provider communication and medication adherence among patients with systemic lupus erythematosus (SLE). The purpose of this study is to optimize the culturally appropriate delivery and test the effect of the CO-LEAD intervention, which includes the following: 1. clinicians will be provided with a program to teach them to use effective communication strategies with patients to review real-time pharmacy refill date, engage and formulate solutions to adherence barriers, and collaboratively overcome adherence barriers. 2. use of a reliable and valid patient-reported measure of the extent of and reasons for nonadherence that helps patients identify and communicate their adherence barriers with clinicians proactively, efficiently, and comprehensively.

CONDITIONS

Official Title

Intervention to Improve Communication and Medication Adherence in Lupus

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • English-speaking and able to provide consent
  • Diagnosed with systemic lupus erythematosus (SLE) and receiving care from enrolled clinicians
  • Prescribed at least one SLE medication and filling medications at a pharmacy linked to Surescripts visible in Epic EMR
Not Eligible

You will not qualify if you...

  • Non-English speakers
  • Patients prescribed only corticosteroids for SLE
  • Patients accompanied by a third party who is unwilling or unable to remain in the waiting room during the patient's visit and who either does not wish to be audio recorded, is a minor without a parental or legal guardian, or is unable to give consent
  • Clinicians involved in the investigators' pilot work at Duke University
  • Clinicians expected to leave their institution within 12 months after enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Duke University

Durham, North Carolina, United States, 27710

Actively Recruiting

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Research Team

K

Kai Sun, MD

CONTACT

K

Kathyrn Pollak, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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