Actively Recruiting

Age: 60Years +
All Genders
Healthy Volunteers
NCT03124303

Interventions for Postoperative Delirium: Biomarker-3

Led by University of Wisconsin, Madison · Updated on 2025-12-15

468

Participants Needed

1

Research Sites

667 weeks

Total Duration

On this page

Sponsors

U

University of Wisconsin, Madison

Lead Sponsor

N

National Institute on Aging (NIA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The IPOD-B3 study aims to characterize the relationship between premorbid brain activity and postoperative delirium in patients undergoing major surgery. This is a expansion of the NeuroVISION Bolt-On study, NCT01980511.

CONDITIONS

Official Title

Interventions for Postoperative Delirium: Biomarker-3

Who Can Participate

Age: 60Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 60 years or older for Cohort 1
  • Age 60 years or younger for Cohort 2
  • Expected hospital stay of at least 2 days after surgery under general or neuraxial anesthesia
  • Written informed consent given before surgery
Not Eligible

You will not qualify if you...

  • Contraindication to EEG
  • Unable or unwilling to attend follow-up appointments
  • History of dementia
  • Unable to provide consent as determined by surgical team
  • Living in a nursing home
  • Undergoing intracranial surgery
  • Unable to complete neurocognitive tests due to language, vision, or hearing problems
  • Unable to communicate with research staff due to language barriers
  • For MRI portion: Contraindications to MRI such as unsafe implanted devices, claustrophobia, or inability to lie still

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
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Trial Site Locations

Total: 1 location

1

University of Wisconsin-Madison

Madison, Wisconsin, United States, 53792

Actively Recruiting

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Research Team

D

David Kunkel, BS

CONTACT

F

Frankie Ingram, BS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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