Actively Recruiting
Intestinal Ischemia Biomarker in Patients With Chronic Mesenteric Ischemia
Led by Oslo University Hospital · Updated on 2025-07-30
180
Participants Needed
1
Research Sites
676 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Plasma Alpha glutathione S transferase (Alpha GST) has been previously demonstrated to be raised in patients with chronic mesenteric ischemia (CMI) caused by atherosclerosis and in patients with median arcuate ligament syndrome (MALS). Raised plasma level of Alpha GST has been demonstrated to decrease or normalize after surgical treatment of patients with CMI and MALS as compared with healthy individuals. This study compares the plasma Alpha GST in patients with CMI and MALS with those with 1-Morbus Crohn, 2-Gallstone disease, and age-matched healthy individuals. Besides, changes in the health-related quality of life (QoL) will be investigated in the study individuals.
CONDITIONS
Official Title
Intestinal Ischemia Biomarker in Patients With Chronic Mesenteric Ischemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age above 18 years and given informed written consent for treatment and study participation
- For MALS group: Diagnosed by CTA or ultrasound and scheduled for surgery
- For CMI group: Diagnosed by CTA or ultrasound and scheduled for surgical or endovascular treatment
- For gallstone disease group: Diagnosed by ultrasound and scheduled for gallbladder removal
- For Crohn disease group: Diagnosed and under gastric lab follow-up
- For healthy control groups: Healthy blood donors with no CMI or MALS confirmed by ultrasound, mean ages 45 and 70 years respectively
You will not qualify if you...
- Age less than 18 years
- Has not given written consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of vascular surgery, Oslo University Hospital
Oslo, Oslo, Norway
Actively Recruiting
Research Team
S
Syed Sajid Hussain Kazmi, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
6
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