Study of Intestinal Microsporidiosis in Heart Transplant Patients in France

What this Trial Is About

This research aims to collect and analyze data on intestinal microsporidiosis in heart transplant patients across France. Microsporidia are microscopic organisms that can cause severe diarrhea, especially in people with weakened immune systems such as organ transplant recipients. While previous studies focused on kidney and liver transplants, this study specifically examines heart transplant recipients to better understand the infections impact and treatment in this group. The study involves a national retrospective review of epidemiological, biological, clinical, and therapeutic information from heart transplant patients diagnosed with intestinal microsporidiosis before the end of 2024. The researchers will gather data including demographics, timing of infection relative to transplant, symptoms, immunosuppressant dosage, and laboratory values at diagnosis and follow-up. Participants are not directly involved since this is an observational study using existing medical records. Researchers will evaluate outcomes such as time to clear infection, weight loss, blood cell counts, and kidney function over one year. The study helps improve understanding of this infection in heart transplant patients and may inform future care. The total duration of follow-up for data collection is one year after diagnosis, with some measurements taken at three months.

Intestinal Microsporidiosis in French Heart Transplant Recipients (CARMIC)