Actively Recruiting
Intra-articular Corticosteroid With Hyaluronic Acid Plus Physiotherapy for Hip Pathologies (NON-OP HIP) - a Randomized Controlled Trial
Led by ArthroBiologix Inc. · Updated on 2025-10-02
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Hip problems like femoroacetabular impingement, labral tears, and mild osteoarthritis can cause pain and limit movement. These conditions often do not require surgery, especially in mild-to-moderate cases, where non-surgical treatments aim to relieve pain, improve function, and delay the need for surgery. While corticosteroid and hyaluronic acid injections are common treatments, their combined effect with physiotherapy has not been well studied. This trial evaluates the impact of adding physiotherapy to combined corticosteroid and hyaluronic acid injections for people with hip conditions. Participants in this study will receive an ultrasound-guided injection of 3 ml hyaluronic acid mixed with 40 mg triamcinolone into their hip joint. One group will also undergo an 8-week physiotherapy program with one visit per week, totaling eight sessions. The other group will receive the injection alone. This design allows comparison of outcomes between those receiving injections plus physiotherapy and those receiving injections only. During the study, participants will be monitored for pain using the Numeric Pain Rating Scale at six months after injection. Other assessments at six months include hip function measured by the International Hip Outcome Tool, quality of life via the EuroQol-5D-5L, medication use, and any adverse events. The study will last up to six months post-injection, with regular follow-up to evaluate the treatments' effects on hip symptoms and overall well-being.
CONDITIONS
Brief Title
Intra-articular Corticosteroid With Hyaluronic Acid Plus Physiotherapy for Hip Pathologies (NON-OP HIP)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 40-60 years old
- Mild hip arthritis (Kellgren-Lawrence grade 2 or lower) with or without a labral tear, femoroacetabular impingement, or mild hip dysplasia
- More than 50% reduction in hip pain after a diagnostic ultrasound-guided intra-articular anaesthetic injection
- Able to pay for private physiotherapy services
- Able to provide informed consent
You will not qualify if you...
- Active infection
- Osteonecrosis of the hip, moderate to severe arthritis (Kellgren-Lawrence grade 3 or higher), or moderate-to-severe hip dysplasia
- Previous fractures of the hip, pelvis, or lower limbs
- Previous surgery on the pelvis, hip, or lower limbs
- Hypermobility disorder or connective tissue disease (e.g., Ehler's-Danlos syndrome, Marfan's syndrome)
- Chronic low back pain and/or sciatica
- Intra-articular steroid hip injection within the past 3 months
- Previous hyaluronic acid injection
- Injuries from motor vehicle collisions
- Injuries from workplace accidents with worker's compensation claims
- Injuries involved in medico-legal disputes
- Pregnant or planning to become pregnant
- Currently enrolled in another study that disallows co-enrollment
- Unable to provide informed consent
- Unable to follow the study protocol
- Contraindications to corticosteroid or hyaluronic acid injections
- Prior enrollment in this study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants receive an ultrasound-guided injection of hyaluronic acid mixed with corticosteroid into their hip joint. Some participants also undergo an 8-week physiotherapy protocol with weekly visits.
1 injection visit and up to 8 physiotherapy visits (once per week)
Duration - Up to 6 months post-injection
Participants are monitored for outcomes and adverse events up to 6 months after the injection.
Visits as scheduled for outcome assessments
Trial Site Locations
Total: 1 location
1
ArthroBiologix
Hamilton, Ontario, Canada
Actively Recruiting
Research Team
S
Steven Phillips
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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