Actively Recruiting

Phase Not Applicable
Age: 40Years - 60Years
All Genders
NCT06653985

Intra-articular Corticosteroid With Hyaluronic Acid Plus Physiotherapy for Hip Pathologies (NON-OP HIP)

Led by ArthroBiologix Inc. · Updated on 2025-10-02

100

Participants Needed

1

Research Sites

130 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Hip pathologies that cause pain and functional limitations are common in the general population. These can include femoroacetabular impingement (FAI), labral tears and mild osteoarthritis (OA) among others. While more severe and symptomatic cases may require surgical intervention, the treatment of mild-to-moderate cases is often treated without surgery to relieve pain, improve function, and delay surgical intervention. Non-operative treatments of hip pathologies consist of a multitude of options. A common non-operative intervention includes intra-articular injections, including corticosteroids and hyaluronic acid. Evidence has demonstrated that corticosteroids have fast acting effects which tend to diminish within a few months, while hyaluronic acid has a delayed time of onset and demonstrates clinical benefit for a longer period of time. Studies have evaluated combinations of corticosteroid and hyaluronic acid, hoping to take advantage of the fast-acting relief of corticosteroid and the longer lasting benefits of corticosteroid. Physiotherapy is also a frequent non-operative intervention used to relieve pain and increase function in patients with hip pathologies. While many studies have looked at intra-articular injections and physiotherapy as independent non-operative possibilities for hip conditions, the combined effect of these two have not received much evaluation. The purpose of this study is to evaluate the effect of physiotherapy in conjunction with a combined corticosteroid and hyaluronic acid intraarticular injection on patient outcomes when compared to a corticosteroid and hyaluronic acid intraarticular injection alone.

CONDITIONS

Official Title

Intra-articular Corticosteroid With Hyaluronic Acid Plus Physiotherapy for Hip Pathologies (NON-OP HIP)

Who Can Participate

Age: 40Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 40 to 60 years old
  • Mild hip arthritis (Kellgren-Lawrence grade 2 or lower) with or without labral tear, femoroacetabular impingement, or mild hip dysplasia
  • More than 50% reduction in hip pain after a diagnostic ultrasound-guided intra-articular anesthetic injection
  • Able to pay for private physiotherapy services
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Active infection
  • Osteonecrosis of the hip, moderate to severe arthritis (Kellgren-Lawrence grade 3 or higher), or moderate to severe hip dysplasia
  • Previous fractures to hip, pelvis, or lower limbs
  • Previous surgery to pelvis, hip, or lower limbs
  • Hypermobility or connective tissue disorders (e.g., Ehler's-Danlos syndrome, Marfan's syndrome)
  • Chronic low back pain or sciatica
  • Received intra-articular steroid hip injection within past 3 months
  • Previous hyaluronic acid injection
  • Injuries from motor vehicle collisions
  • Workplace injuries with worker's compensation claims
  • Injuries involved in medico-legal disputes
  • Pregnant or planning pregnancy
  • Enrolled in conflicting studies
  • Unable to give informed consent
  • Unable to follow study protocol
  • Contraindications to corticosteroid or hyaluronic acid injection
  • Prior enrollment in this study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

ArthroBiologix

Hamilton, Ontario, Canada

Actively Recruiting

Loading map...

Research Team

S

Steven Phillips

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Intra-articular Corticosteroid With Hyaluronic Acid Plus Physiotherapy for Hip Pathologies (NON-OP HIP) | DecenTrialz