Actively Recruiting
Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP
Led by Northwestern University · Updated on 2023-09-13
138
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Holmium Laser Enucleation of the Prostate (HoLEP) is a size-independent treatment option for benign prostatic hypertrophy (BPH) as recommended by the American Urological Association (AUA) Guidelines. Loop diuretics (furosemide) have been given historically during the morcellation portion of HoLEP to promote urine production in the post-operative setting and to minimize the impact of fluid absorption during long periods of morcellation. The intra-operative use of 20mg IV furosemide in perioperative HoLEP pathways has been propagated with the dissemination of HoLEP across North America without evidence to support its routine administration. With increasing surgical efficiency from improvements in laser and morcellator technology, the role of intra-operative furosemide is unknown. This study is designed to assess if there is a significant difference in same day discharge rates after Holmium Laser Enucleation of the Prostate (HoLEP) with and without IV furosemide. .
CONDITIONS
Official Title
Intra-operative Loop Diuretics to Improve Same-day Discharge Rates After HoLEP
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males 18 to 89 years old undergoing HoLEP
- Willing to sign the Informed Consent Form
- Able to read, understand, and complete patient questionnaires
You will not qualify if you...
- Allergy or hypersensitivity to furosemide or other loop diuretics
- Anuric patients or patients with liver failure
- Patients undergoing concurrent ureteroscopy with or without laser lithotripsy, percutaneous nephrolithotomy, or non-urologic surgery at the time of HoLEP
- Anticipated need for perineal urethrostomy during HoLEP
- Patients not undergoing catheter removal and voiding trial at Northwestern Memorial Hospital
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
Research Team
N
Nicholas S Dean, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here