Actively Recruiting
Intra-wound Vancomycin Powder for Prevention of Surgical Site Infection Following Spinal Surgery
Led by Rabin Medical Center · Updated on 2024-11-27
363
Participants Needed
1
Research Sites
339 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cefazolin is given routinely pre and intraoperatively for patients undergoing spinal surgery to reduce the rate of infection. Intra-wound admission of Vancomycin powder has been suggested to reduce wound infection rates. Therefore, this study aims to compare the rate of wound-related complications between patients receiving standard treatment compared to patients receiving an addition of topical Vancomycin and to identify the optimal Vancomycin dosage. All groups will receive the recommended regimen of routine IV antibiotic prophylaxis.
CONDITIONS
Official Title
Intra-wound Vancomycin Powder for Prevention of Surgical Site Infection Following Spinal Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing posterior spinal fusion operation at the neurosurgery department at the Rabin Medical Center
- Ability to understand and sign written informed consent by the patient or legal guardian
You will not qualify if you...
- Preoperative ongoing infectious disease as judged by the primary surgeon
- Receiving ongoing antibiotic treatment for other infections
- Allergy or sensitivity to vancomycin or cefazolin
- Previous spine surgery at the same level within the last 90 days
- Need for postoperative radiotherapy at the surgical site
- Stage 4 chronic kidney disease with glomerular filtration rate 15-30 ml/min or worse
- Undergoing spinal decompression only
- Trauma patients
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Rabin Medical Center
Petah Tikva, Israel
Actively Recruiting
Research Team
E
Eyal Itshayek, MD
CONTACT
S
Shani Berkowitz, Msc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here