Actively Recruiting
Intracervical Vasopressin
Led by Prisma Health-Upstate · Updated on 2025-11-04
50
Participants Needed
1
Research Sites
56 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized study looks at whether using a medicine injected into the cervix of the uterus (intracervical), called vasopressin, helps to achieve better removal of retained products of conception (RPOC). RPOC means that after a pregnancy has ended (through miscarriage, abortion, or delivery), some parts of the pregnancy tissue, usually from the placenta or fetus, have stayed in the uterus. A hysteroscopic removal of RPOC is one type of treatment. This is a surgical procedure where a doctor uses a small camera attached to a thin tube (called a hysteroscope) to look inside the uterus. The main goal of the study is : • To add to the existing research through this study to see if the injection of intracervical vasopressin leads to improved completion rates of hysteroscopic management of RPOC. Participants will: • would be randomized to receive either vasopressin intracervical injection or a placebo injection (non-active saline) during your procedure. Information from the procedure will be collected from the participant's medical record.
CONDITIONS
Official Title
Intracervical Vasopressin
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women
- Aged 18-51 years
- Undergoing surgical management for retained products of conception, postpartum retained products of conception or 1st trimester missed or incomplete abortion
You will not qualify if you...
- Hemodynamic instability
- Active hemorrhage, such as soaking a pad every hour
- Allergy to vasopressin
- Concern for intrauterine arteriovenous malformation
- Inability to consent
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The OB/GYN Center
Greenville, South Carolina, United States, 29605
Actively Recruiting
Research Team
P
Patti Parker, BSN
CONTACT
P
Paul Miller, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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