Actively Recruiting

Phase 1
Age: 20Years - 80Years
All Genders
NCT05724576

Intracoronary Administration of OmniMSC-AMI for Acute ST-segment Elevation Myocardial Infarction Patients

Led by Taiwan Bio Therapeutics Inc. · Updated on 2025-06-06

10

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will test the hypothesis intracoronary administration of OmniMSC-AMI (allogenic bone marrow-derived mesenchymal stem cells) just after finishing the primary percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) patients without cardiogenic shock is safe and may provide benefit on improving left ventricular ejection fraction (LVEF) during clinical follow-up.

CONDITIONS

Official Title

Intracoronary Administration of OmniMSC-AMI for Acute ST-segment Elevation Myocardial Infarction Patients

Who Can Participate

Age: 20Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 20 to 80 years old
  • Diagnosed with ST-elevation myocardial infarction (anterior myocardial infarction) confirmed by chest pain onset, 12-lead EKG showing ST-segment elevation in V1-V6 leads of at least 1 mm, and elevated TnT-I levels
  • Presenting within 6 hours of acute myocardial infarction onset
  • Willing to receive treatment and sign informed consent
Not Eligible

You will not qualify if you...

  • Age below 20 or above 80 years old
  • History of malignancy
  • History of sepsis with abnormal white blood cell count
  • History of hematologic disorders
  • History of AIDS
  • Advanced liver cirrhosis
  • Chronic kidney disease stage 5 with creatinine clearance less than 15 ml/min
  • Acute myocardial infarction occurrence more than 6 hours prior
  • Non-first acute myocardial infarction
  • Pregnancy or breastfeeding
  • Prisoner status
  • Cancer treatment within the past 2 years
  • Expected lifespan less than 6 months
  • Evaluated as unsuitable candidate by principal investigator
  • Currently participating in other clinical trials

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Kaohsiung Chang Gung Memorial Hospital

Kaohsiung City, Taiwan

Actively Recruiting

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Research Team

T

Timothy Huang, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

2

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Intracoronary Administration of OmniMSC-AMI for Acute ST-segment Elevation Myocardial Infarction Patients | DecenTrialz