Actively Recruiting

Early Phase 1
Age: 0 - 48Hours
All Genders
NCT06746532

Intranasal Breast Milk Therapy in HIE

Led by Semmelweis University · Updated on 2024-12-24

80

Participants Needed

1

Research Sites

304 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is an open-label prospective single-center randomized controlled trial to evaluate the effect of intranasal breast milk in hypoxic-ischemic encephalopathic neonates receiving therapeutic hypothermia on long term neurodevelopmental outcome compared to standard care.

CONDITIONS

Official Title

Intranasal Breast Milk Therapy in HIE

Who Can Participate

Age: 0 - 48Hours
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Moderate or severe hypoxic-ischemic encephalopathy receiving therapeutic hypothermia
  • Gestational age of at least 35 weeks
  • Less than 48 hours old at enrollment
  • Receiving hypothermia treatment for 72 hours
  • Parental consent obtained
Not Eligible

You will not qualify if you...

  • Presence of congenital malformations
  • Concurrent cerebral lesions
  • Receiving ECMO therapy
  • Contraindications to lactation
  • Mother unable or unwilling to provide fresh breast milk
  • Postpartum asphyxia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Neonatology, Pediatric Center, Semmelweis University, Budapest, Hungary

Budapest, Hungary, 1083

Actively Recruiting

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Research Team

U

Unoke Meder, MD, PhD

CONTACT

A

Agnes Jermendy, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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