Actively Recruiting

Phase 2
Age: 21Years - 65Years
All Genders
NCT04044534

Intranasal Insulin for Posttraumatic Stress Disorder

Led by VA Connecticut Healthcare System · Updated on 2025-09-16

20

Participants Needed

1

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To evaluate if intranasal insulin is effective in reducing PTSD symptoms.

CONDITIONS

Official Title

Intranasal Insulin for Posttraumatic Stress Disorder

Who Can Participate

Age: 21Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female, 21-65 years old
  • Current PTSD
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Unstable medical condition, clinically determined by a physician
  • Diabetes requiring insulin or oral hypoglycemic agents
  • Moderate-severe traumatic brain injury
  • Current psychotic disorder, bipolar disorder, cognitive disorder in the past 12 months
  • Current substance use disorders (except alcohol, tobacco, or cannabis) in the past 3 months
  • Changes in doses of psychotropic medications in the past 4 weeks
  • Initiation of individual therapy or counseling in the past 4 weeks
  • Imminent suicidal or homicidal risk
  • Contraindication to Insulin
  • History of claustrophobia
  • Presence of cardiac pacemaker or other electronic device or ferromagnetic metal foreign bodies in vulnerable positions as assessed by a standard pre-MRI safety screening questionnaire

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

VA Connecticut Healthcare System

West Haven, Connecticut, United States, 06516

Actively Recruiting

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Research Team

G

Gihyun Yoon, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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