Actively Recruiting

Age: 18Years +
FEMALE
NCT07131735

Intraoperative Detection of Breast Cancer by Electrosurgical Gas Analysis and Artificial Intelligence

Led by Pontificia Universidad Catolica de Chile · Updated on 2025-08-20

30

Participants Needed

2

Research Sites

91 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this clinical trial is to assess the feasibility of training a device capable of distinguishing various gases emitted by tissues cauterized by an electrosurgical unit during a breast cancer resection surgery. The patients to be enrolled will be women over 18 years old diagnosed with breast cancer who are indicated for conservative breast cancer resection surgery as treatment. The main questions to be answered are: The specificity and sensitivity of the device in detecting margins compromised with tumor cells in resection surgeries. Evaluate the applicability of the device in breast cancer surgeries for real-time detection of margins. Evaluate the differences in the pattern of gases emitted in tumor cells vs normal cells. By consenting, the study patients will allow the investigative team to access the clinical record, results of images, post-surgical biopsies, recording of the surgery while preserving the patient's anonymity, and the installation of the gas detection device. This device does not alter the flow of the surgery and does not add additional risk to it.

CONDITIONS

Official Title

Intraoperative Detection of Breast Cancer by Electrosurgical Gas Analysis and Artificial Intelligence

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically confirmed diagnosis of malignant breast cancer
  • Scheduled for breast-conserving surgery at the Hospital UC
  • Able and willing to provide informed consent
Not Eligible

You will not qualify if you...

  • Pregnant or lactating women
  • Known allergy or hypersensitivity to any component of the BCGC device
  • Participation in another interventional clinical trial within 30 days prior to enrollment

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Trial Site Locations

Total: 2 locations

1

Hospital Clínico UC CHRISTUS

Santiago, Santiago Centro, Chile, 8320000

Actively Recruiting

2

Facultad de medicina UC

Santiago, Santiago Metropolitan, Chile, 8330191

Active, Not Recruiting

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Research Team

M

Maximiliano L Mariné

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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