Using EEG to Detect and Predict Cognitive Problems After Non-Cardiac Surgery in Adults Under General Anesthesia

What this Trial Is About

Postoperative neurocognitive disorders PND are serious complications that often occur after surgery, particularly in older adults. These disorders can affect cognitive functions like memory and attention for years, lowering quality of life and increasing hospital stays and medical costs. One common form, postoperative delirium POD, involves disturbances in consciousness and cognition and is thought to arise from a mix of risk factors. Diagnosing PND is difficult due to varied symptoms and a lack of clear criteria or biomarkers. This observational study evaluates the use of intraoperative electroencephalography EEG to identify neurocognitive complications during surgery. Patients scheduled for intermediate to high-risk non-cardiac surgery under general anesthesia will have EEG recorded with a 16-electrode setup. Researchers aim to analyze EEG patterns, such as alpha rhythm power and burst suppression, to predict risks of postoperative delirium, early neurocognitive disorders, and silent brain infarction. Participants will undergo EEG monitoring during surgery and be followed for up to three years to assess cognitive outcomes and mortality. Researchers will collect data on intraoperative EEG signals and evaluate their prognostic value for postoperative complications. The study includes various cognitive and neurological assessments and tracks outcomes like delirium development and brain infarction, providing long-term insight into surgery-related brain health risks.

Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic Analysis