Actively Recruiting
Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia
Led by Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · Updated on 2026-04-01
206
Participants Needed
1
Research Sites
264 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This randomized clinical trial compares the hemodynamic effects of general anesthesia versus combined general anesthesia (thoracic epidural) in patients undergoing pancreatoduodenectomy. The primary aim is to assess the incidence of intraoperative hypotension and related adverse events. Secondary outcomes includes vasopressor requirements, transfusion needs, postoperative complications, intensive care unit admission, hospital length of stay, and mortality.
CONDITIONS
Official Title
Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed written informed consent
- Scheduled for elective pancreatoduodenectomy at National Institute of Medical Sciences and Nutrition Salvador Zubirán
- No contraindications for epidural anesthesia including no infection at puncture site, no thrombocytopenia, no coagulation disorders, no intracranial hypertension, and no patient refusal
You will not qualify if you...
- Under 18 years of age
- Pregnancy
- Inability to randomize due to contraindications to epidural use or other specific circumstances
AI-Screening
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Trial Site Locations
Total: 1 location
1
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Mexico City, Mexico City, Mexico, 14080
Actively Recruiting
Research Team
R
Rafael P. Leal Villalpando, MD
CONTACT
D
Diana E. Díaz Arizmendi, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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