Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
NCT07108764

Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries

Led by Tanta University · Updated on 2025-08-07

100

Participants Needed

1

Research Sites

102 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to compare the effect of intraoperative infusion of either lidocaine or dexmedetomidine on the incidence of postoperative delirium (POD) in elderly patients undergoing major surgeries. It also aims to evaluate the impact of both medications on intraoperative regional cerebral oxygen saturation (rSO₂).

CONDITIONS

Official Title

Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 65 years or older
  • Both sexes
  • Physical status classification II - III according to the American Society of Anesthesiologists (ASA)
  • Undergoing elective non-cardiac surgeries
Not Eligible

You will not qualify if you...

  • History of mental illness, neurological illness, or scoring less than 8 on the abbreviated mental test before operation
  • Severe hearing or visual impairment that may interfere with communication
  • Severe renal or hepatic dysfunction
  • Use of central nervous system medications such as antipsychotics, anticonvulsants, antiparkinsonian drugs, or antidepressants
  • Contraindications to lidocaine or dexmedetomidine including allergy, severe bradycardia, or atrioventricular (AV) block

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Tanta University

Tanta, El-Gharbia, Egypt, 31527

Actively Recruiting

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Research Team

D

Dina H Alhassanin, Master

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries | DecenTrialz