Using Microscope Integrated Optical Coherence Tomography to Improve Eye Surgery and Imaging Evaluation in Healthy Volunteers, Surgeons, and Surgical Patients

What this Trial Is About

This research aims to develop and evaluate a new technology called microscope integrated optical coherence tomography MIOCT that provides live, three-dimensional imaging during eye surgeries. The goal is to improve how surgeries are performed and their outcomes by offering better visualization, which could enable new types of eye and microsurgeries currently limited by existing imaging methods. The study involves several groups healthy adults with normal eye health who will have images taken to test and improve the MIOCT system, eye surgeons who will use the device during practice surgeries to assess its usefulness, and adult and minor patients undergoing actual eye surgeries where MIOCT imaging will be used during the procedures. The device uses a near-infrared light beam integrated into the surgical microscope and does not touch the eye. Participants will be involved through imaging sessions or during their surgeries, depending on their group. Researchers will collect multiple detailed images of the retina, cornea, and blood vessels, and compare these images before and after surgical steps. They will assess image quality, vascular flow, eye structure changes, and fluid volume related to retinal detachment. The study includes follow-up to monitor these outcomes, with participation lasting according to the imaging or surgical schedule.

Intraoperative OCT Guidance of Intraocular Surgery II