Observational Study on Intraoperative Paravertebral Block to Reduce Complications After Thoracic Surgery

What this Trial Is About

Researchers are evaluating the relationship between intraoperative paravertebral nerve blocks and the reduction of complications after thoracic surgery. This observational study includes both retrospective and prospective parts and focuses mainly on patients undergoing pulmonary and mediastinal thoracic surgeries. The goal is to explore how this nerve block might influence postoperative outcomes and identify related biochemical markers. Participants are divided into two groups one receives a paravertebral nerve block under ultrasound guidance during surgery targeting the thoracic vertebrae related to the surgical site, using standard local anesthetics. The other group receives standard pain management without the nerve block, following usual institutional protocols. Both groups undergo thoracic surgery with standard anesthesia and monitoring. Retrospective data from previous surgeries with nerve blocks will also be analyzed. During the prospective part, researchers will collect biochemical markers like MMP3, neutrophils, leukocytes, PCT, and CRP around the surgery time. They will assess postoperative pain and cough scores, and record time to first flatus and defecation at 24 and 48 hours after surgery. Participants will be followed for 30 days to track complications. The study aims to correlate biomarkers with clinical outcomes to evaluate prognosis after thoracic surgery.

Intraoperative Paravertebral Block and Postoperative Complications