Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT04752137

Intraoperative Tumor Margin Identification With ICG Dye Imaging

Led by Massachusetts General Hospital · Updated on 2026-04-24

100

Participants Needed

1

Research Sites

409 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this research study we want to learn more about the use of indocyanine green (ICG) during bone or soft tissue mass resections. Indocyanine green (ICG) is a type of dye that is used in medical diagnostics. We want to determine if ICG-guided tumor resection is more effective in obtaining negative margins. Lastly, we want to assess traditional oncologic outcomes of local recurrence, time to metastatic disease, and overall and disease specific survival.

CONDITIONS

Official Title

Intraoperative Tumor Margin Identification With ICG Dye Imaging

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients 18 years or older
  • Diagnosed with a benign or malignant bone or soft tissue mass
  • Scheduled for surgery at Massachusetts General Hospital Department of Orthopaedic Surgery
  • Able to provide consent during the study period
Not Eligible

You will not qualify if you...

  • Pregnant or nursing patients
  • Known severe allergy or anaphylaxis to IV contrast or iodine
  • Patients with kidney failure not cleared for ICG administration by their primary physician or oncologist

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

S

Santiago A Lozano-Calderon, MD, PhD

CONTACT

S

Shreya Halur, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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