Study of Intraoral Cryotherapy to Improve Anesthesia in Mandibular Incisor Teeth with Irreversible Pulpitis

What this Trial Is About

Researchers are evaluating the effectiveness of intraoral cryotherapy compared to supplemental lingual infiltration anesthesia alongside buccal infiltration anesthesia in patients with symptomatic irreversible pulpitis affecting mandibular incisor teeth. This study aims to improve anesthetic success, as inflammation in these teeth often reduces the effectiveness of conventional anesthesia. The research also examines the impact of using anesthetic solutions with or without vasoconstrictors on pain control during treatment. Participants are randomly assigned to one of seven groups receiving various combinations of buccal infiltration, lingual infiltration, and intraoral cryotherapy, using lidocaine with or without vasoconstrictors. Intraoral cryotherapy involves applying cold packs to the vestibular sulcus for about five minutes before anesthesia. The trial compares these methods to assess which combination offers better pain relief and anesthetic success during endodontic procedures. During the study, participants will undergo electric pulp testing and report pain levels using the Numerical Rating Scale and Wong-Baker FACES scale throughout anesthesia administration and pulpectomy treatments lasting up to 30 minutes. Thermal imaging will monitor temperature changes in the oral tissues to better understand tissue responses. The primary outcome measures include anesthetic success rates during treatment, while secondary outcomes assess pain intensity during the procedures. This phase 4 study is expected to provide valuable insights into improving anesthesia for mandibular incisors with irreversible pulpitis.

Intraoral Cryotherapy on Anesthetic Efficacy in Mandibular Incisors