Actively Recruiting
Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation
Led by Dana-Farber Cancer Institute · Updated on 2025-12-15
20
Participants Needed
1
Research Sites
214 weeks
Total Duration
On this page
Sponsors
D
Dana-Farber Cancer Institute
Lead Sponsor
T
THOR Photomedicine Ltd
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a single center pilot study evaluating intraoral photobiomodulation for the prevention of oral mucositis in patients undergoing myeloablative allogeneic hematopoietic cell transplantation (alloHCT). Patients who are planned for alloHCT will receive daily intraoral photobiomodulation therapy (PBMT) using a novel LED device. The name of the study device involved in this study is: \- THOR LX2.3 with LED Lollipop
CONDITIONS
Official Title
Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Planned to undergo myeloablative allogeneic HCT using FluBu4 conditioning and Tac-Mtx GVHD prophylaxis.
- Age 18 years or older.
- Able to understand and willing to sign informed consent.
You will not qualify if you...
- Received intraoral photobiomodulation therapy within 4 weeks before admission for HSCT.
- History of radiation therapy to the head and neck.
- History of photosensitivity or diseases causing photosensitivity.
- Planned treatment with palifermin for oral mucositis prevention.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02115
Actively Recruiting
Research Team
K
Kentaro Ikeda, DDS,MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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