Comparing Computer-Assisted Intraosseous and Infiltration Anesthesia for Treating Molar-Incisor Hypomineralization in Children

What this Trial Is About

Researchers are evaluating the clinical effectiveness of two anesthesia techniquescomputer-assisted intraosseous and infiltration anesthesiain children aged 6 to 12 years with Molar-Incisor Hypomineralization MIH affecting their permanent first molars. The study compares these methods during restorative dental treatments by measuring pain levels, behavioral responses, pulse rates, and salivary chromogranin A levels, aiming to find a minimally invasive and effective anesthesia approach for this sensitive condition. The study involves 30 children who receive both anesthesia methods in separate sessions spaced at least one week apart. Each session includes anesthesia administration using the SleeperOne 5 device on either the right or left upper first permanent molar, followed by removal of carious tissue and restorative treatment. The order of anesthesia types is randomized, and the opposite side molar receives the alternative technique in a third session. Participants will have their pain assessed using the Visual Analogue Scale VAS, behavior observed with the FLACC scale, and pulse rate monitored throughout the procedures. Saliva samples are collected before anesthesia, after anesthesia application, and post-treatment for biochemical analysis. Behavioral responses are video recorded for unbiased evaluation. The study will measure the need for additional anesthesia and overall anesthesia efficacy, with all data collected over multiple visits to inform best clinical practices.

Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children