Actively Recruiting

Phase 4
Age: 18Years - 40Years
All Genders
NCT06511232

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

Led by The Methodist Hospital Research Institute · Updated on 2026-04-09

84

Participants Needed

1

Research Sites

258 weeks

Total Duration

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AI-Summary

What this Trial Is About

The purpose of this study is to determine if intraosseous (IO) morphine decreases pain and post-operative opioid use in patients undergoing anterior cruciate ligament (ACL) reconstruction.

CONDITIONS

Official Title

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

Who Can Participate

Age: 18Years - 40Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients of the IRB approved surgeon(s) undergoing ACL reconstruction with bone-to-bone (BTB) autograft
  • Patients aged between 18-40 years old at the time of surgery
Not Eligible

You will not qualify if you...

  • Patients undergoing ACL reconstruction with any other type of autograft or allograft other than BTB
  • Patients younger than 18 years old or older than 40 years old
  • Patients undergoing meniscal root repair or any other repair that changes their weight-bearing status
  • Patients with a history of substance abuse
  • Vulnerable populations
  • Patients on chronic pain medication within the last 6 months
  • BMI �35
  • Allergy to morphine
  • Unwilling to participate
  • Any additional reason the PI deems reasonable

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Houston Methodist Research Institute

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

H

Haley Goble, MHA

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction | DecenTrialz