Actively Recruiting

Phase 4
Age: 18Years - 65Years
FEMALE
Healthy Volunteers
NCT04130464

Intraperitoneal Infusion of Analgesic for Postoperative Pain Management

Led by Ying Liu · Updated on 2026-04-09

120

Participants Needed

2

Research Sites

374 weeks

Total Duration

On this page

Sponsors

Y

Ying Liu

Lead Sponsor

A

Avanos Medical

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study is a prospective, double-blinded, placebo-controlled multi-center trial to measure if postoperative pain and the amount of narcotics used are reduced by a clinically significant amount in women undergoing minimally invasive hysterectomy receiving a continuous infusion of intraperitoneal (IP) local anesthetic (LA) or a continuous infusion of LA combined with an NSAID compared with a control group who receives only 0.9% normal saline.

CONDITIONS

Official Title

Intraperitoneal Infusion of Analgesic for Postoperative Pain Management

Who Can Participate

Age: 18Years - 65Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Planned hysterectomy for a benign gynecologic reason (no cancer concerns)
  • Scheduled surgery with a fellowship-trained minimally invasive gynecologic surgeon at a study site
  • Planned robotic assisted total laparoscopic hysterectomy (RA-TLH) or total laparoscopic hysterectomy (TLH)
  • Able to provide informed consent
  • Able to complete questionnaires
Not Eligible

You will not qualify if you...

  • Concern for malignancy
  • Surgery scheduled outside the minimally invasive gynecologic surgery department
  • Allergy to ketorolac or ropivacaine
  • Currently enrolled in another pain management study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

MedStar Washington Hospital Center

Washington D.C., District of Columbia, United States, 20010

Actively Recruiting

2

The GW Medical Faculty Associates

Washington D.C., District of Columbia, United States, 20037

Actively Recruiting

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Research Team

R

Radwa Aly

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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