Actively Recruiting
Intrapleural Nebulization of Bupivacain to Reduce Postoperative Pain
Led by Assiut University · Updated on 2024-05-20
60
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Thoracic surgery is now common and as other surgeries evolution of minimally invasive techniques is employed. Video-assisted thoracic surgery (VATS) produces little scar but may produce severe pain that may affect the pulmonary function. Many procedure was developed like intercostal nerve block which require injections at multiple levels, Insertion of local anaesthetic (LA) in the surgical drain but that was dangerous due to the large amount of LA and not sufficient to completely eliminate pain. Bupvicaine nebulization, through surgical port which won't make any other wound, thought to be sufficient because Nebulization will enable us better distribution and less amounts of LA. Bupvicaine is local anaesthetic amide group that works by blocking sodium channels thus preventing progression of action potential.
CONDITIONS
Official Title
Intrapleural Nebulization of Bupivacain to Reduce Postoperative Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients classified as American Society of Anesthesiologists class 1 to 3
- Scheduled for video-assisted thoracic surgery (VATS) under general anesthesia
You will not qualify if you...
- Allergy to local anesthetics
- Pleural inflammation due to recent pneumonia
- Unable or unwilling to perform spirometer test
- Renal dysfunction with elevated creatinine greater than 2 mg/dl
- Hepatic dysfunction with elevated liver enzymes three times above normal
- History of addiction
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Assiut University
Asyut, Assuit, Egypt, 880
Actively Recruiting
Research Team
E
Esam Moubarak Sahin
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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