Actively Recruiting
Intrapleural Ropivacaine Infusion in Cardiac Surgery
Led by Saint Petersburg State University, Russia · Updated on 2026-03-10
116
Participants Needed
2
Research Sites
110 weeks
Total Duration
On this page
Sponsors
S
Saint Petersburg State University, Russia
Lead Sponsor
P
Primorsky Regional Clinical Hospital No. 1
Collaborating Sponsor
AI-Summary
What this Trial Is About
For many patients, a primary source of postoperative pain following cardiac surgery is the presence of pleural drains, which the surgeon places at the end of the operation and maintains for 1 to 3 days. One promising method of pain management after cardiac surgery is interpleural analgesia, particularly when traditional analgesic methods, such as systemic opioids or epidural anesthesia, may be limited due to the risk of complications. Interpleural analgesia involves the introduction of local anesthetics directly into the pleural cavity through drainage tubes placed after cardiac surgery. This method targets pain receptors in the chest area, providing effective analgesia without significant systemic effects. Several clinical studies have confirmed the safety and efficacy of intrapleural administration of anesthetics after thoracic surgery. The aim of this randomised double-blind placebo controlled study is to test the hypothesis that, in patients after cardiac surgery, the quality of recovery from anesthesia with intrapleural use of ropivacaine is superior to that with a placebo.
CONDITIONS
Official Title
Intrapleural Ropivacaine Infusion in Cardiac Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled cardiac surgery using a standard median sternotomy
- Planned opening of the pleural cavities
- Age more than 18 years
- Signed informed consent to participate in the study
You will not qualify if you...
- Contraindications for ropivacaine
- Redo surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Saint-Petersburg university hospital
Saint Petersburg, Russia
Actively Recruiting
2
Primorskiy general hospital #1
Vladivostok, Russia
Actively Recruiting
Research Team
S
Sergey M Efremov, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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