Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT07116343

Intrapleural Ropivacaine Infusion in Cardiac Surgery

Led by Saint Petersburg State University, Russia · Updated on 2026-03-10

116

Participants Needed

2

Research Sites

110 weeks

Total Duration

On this page

Sponsors

S

Saint Petersburg State University, Russia

Lead Sponsor

P

Primorsky Regional Clinical Hospital No. 1

Collaborating Sponsor

AI-Summary

What this Trial Is About

For many patients, a primary source of postoperative pain following cardiac surgery is the presence of pleural drains, which the surgeon places at the end of the operation and maintains for 1 to 3 days. One promising method of pain management after cardiac surgery is interpleural analgesia, particularly when traditional analgesic methods, such as systemic opioids or epidural anesthesia, may be limited due to the risk of complications. Interpleural analgesia involves the introduction of local anesthetics directly into the pleural cavity through drainage tubes placed after cardiac surgery. This method targets pain receptors in the chest area, providing effective analgesia without significant systemic effects. Several clinical studies have confirmed the safety and efficacy of intrapleural administration of anesthetics after thoracic surgery. The aim of this randomised double-blind placebo controlled study is to test the hypothesis that, in patients after cardiac surgery, the quality of recovery from anesthesia with intrapleural use of ropivacaine is superior to that with a placebo.

CONDITIONS

Official Title

Intrapleural Ropivacaine Infusion in Cardiac Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled cardiac surgery using a standard median sternotomy
  • Planned opening of the pleural cavities
  • Age more than 18 years
  • Signed informed consent to participate in the study
Not Eligible

You will not qualify if you...

  • Contraindications for ropivacaine
  • Redo surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 2 locations

1

Saint-Petersburg university hospital

Saint Petersburg, Russia

Actively Recruiting

2

Primorskiy general hospital #1

Vladivostok, Russia

Actively Recruiting

Loading map...

Research Team

S

Sergey M Efremov, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here