Actively Recruiting
IntraRenal HEmoDynamics to IntegraTE CA-AKI Risk and Monitor NephroprotectiIoN by ImpElla Support.
Led by Heinrich-Heine University, Duesseldorf · Updated on 2024-09-19
550
Participants Needed
2
Research Sites
87 weeks
Total Duration
On this page
Sponsors
H
Heinrich-Heine University, Duesseldorf
Lead Sponsor
G
German Heart Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
the hypothesis is that elevation of the intrarenal resistive index (RI) characterizes patients at elevated risk for subsequent CA-AKI and integrates items of the Mehran AKI risk score into a single, readily obtainable parameter. Impella-mediated nephroprotection confers to reduction of elevated RI by restoration of intrarenal venous flow profile.
CONDITIONS
Official Title
IntraRenal HEmoDynamics to IntegraTE CA-AKI Risk and Monitor NephroprotectiIoN by ImpElla Support.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years and older but less than 90 years
- Scheduled for PCI or protected PCI within the next week or on the same day
You will not qualify if you...
- Severe chronic kidney disease with eGFR 20 ml/min or less or on dialysis
- Acute kidney injury within the last seven days or ongoing acute kidney injury
- STEMI within 24 hours from symptom onset or with mechanical complications
- Cardiogenic shock with low blood pressure unresponsive to fluids or requiring support
- Cardiorespiratory arrest related to current admission unless stable and recovered
- Platelet count below 75,000 cells/mm3 or bleeding disorders
- Pregnant or of child-bearing potential without recent negative pregnancy test
- Participation in another clinical study with investigational drug or device
- Medical or psychiatric conditions preventing informed consent or follow-up
- Non-cardiac conditions with life expectancy less than 1 year
- Belonging to a vulnerable population unable to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Department of Cardiology, Angiology and Intensive Care Medicine Campus at German Heart Center Charite
Berlin, Germany
Actively Recruiting
2
Division of Cardiology, Pulmonary Disease and Vascular Medicine at University Hospital Duesseldorf
Düsseldorf, Germany, 40225
Actively Recruiting
Research Team
A
Amin Polzin, Prof.
CONTACT
L
Lisa Dannenberg, PD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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