Comparison of Intrathecal Epinephrine Versus Dexmedetomidine as Additives in Spinal Anesthesia During Cesarean Section

What this Trial Is About

Researchers are evaluating the use of two different drugs, dexmedetomidine and epinephrine, added to a standard spinal anesthesia mixture for cesarean section. The study aims to determine if dexmedetomidine is not worse than epinephrine in providing effective spinal analgesia during cesarean deliveries. This research addresses a gap, as no prior studies have directly compared these two drugs as additives in single-dose spinal analgesia. Participants will receive either 5 mcg of dexmedetomidine or 200 mcg of epinephrine added to the standard spinal mixture, which includes hyperbaric bupivacaine and morphine. This is a randomized, quadruple-blinded study comparing these two active treatments. The spinal anesthesia is given as a single shot during scheduled cesarean sections. During the study, participants will be closely monitored for sensory recovery time, pain levels at various stages of surgery, blood pressure, heart rate, and other vital signs up to 270 minutes after spinal anesthesia. Researchers will also assess opioid use, patient satisfaction, newborn Apgar scores, and any side effects like nausea or shivering. The total study participation includes monitoring during surgery and follow-up assessments up to 24 hours after the procedure.

Intrathecal Dexmedetomidine vs Epinephrine