Actively Recruiting
Intrathecal Dexmedetomidine vs Epinephrine
Led by Icahn School of Medicine at Mount Sinai · Updated on 2026-01-07
62
Participants Needed
1
Research Sites
75 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Several studies have shown that adding dexmedetomidine or epinephrine to single-dose spinal analgesia preparations improves the length and/or speed of onset of the sensory block and post-operative pain management without increased negative side effects. To date, however, no study has compared adjunctive intrathecal dexmedetomidine to adjunctive intrathecal epinephrine in single-dose spinal analgesia. The purpose of this study is to determine if adjunctive intrathecal dexmedetomidine is non-inferior to adjunctive intrathecal epinephrine in providing better single-dose spinal analgesia during cesarean section.
CONDITIONS
Official Title
Intrathecal Dexmedetomidine vs Epinephrine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant patients
- Aged 18-55 years
- Scheduled for primary or secondary cesarean section
- Candidates for single-dose spinal anesthesia
- Singleton pregnancy
You will not qualify if you...
- Refusal of spinal anesthesia
- Not a candidate for spinal anesthesia due to coagulopathy, elevated intracranial pressure, infection at injection site, or similar conditions
- Emergency cesarean section
- Preexisting motor or sensory deficits
- Suspected pre-eclampsia
- Receiving combined spinal-epidural anesthesia
- Body mass index (BMI) over 40
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Mount Sinai Hospital
New York, New York, United States, 10029
Actively Recruiting
Research Team
T
Talia Scott, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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