Actively Recruiting

Age: 18Years - 90Years
All Genders
NCT05862558

Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR

Led by Baylor Research Institute · Updated on 2026-01-13

50

Participants Needed

1

Research Sites

165 weeks

Total Duration

On this page

Sponsors

B

Baylor Research Institute

Lead Sponsor

S

Shockwave Medical, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

To assess the efficacy and safety of Intravascular Lithotripsy (IVL) in subjects undergoing transfemoral TAVR in patients with severe iliac disease, prohibitive for transfemoral TAVR in patients with severe symptomatic aortic stenosis, otherwise considered for alternative access TAVR. (e.g. trans-carotid)

CONDITIONS

Official Title

Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 90 years at the time of signing informed consent
  • Iliofemoral disease requiring treatment due to more than 50% stenosis and heavy calcification of the iliac arteries
  • Severe symptomatic aortic stenosis with planned TAVR procedure
  • Prohibitive iliofemoral disease confirmed by diagnostic CT scan of abdomen and pelvis
  • Ability to provide written informed consent
Not Eligible

You will not qualify if you...

  • Participation in another research study involving an investigational agent without reaching the primary endpoint
  • Contraindications to Intravascular Lithotripsy (IVL)
  • Contraindications or ineligibility for transcatheter aortic valve replacement (TAVR)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Baylor Scott and White Heart Hospital

Plano, Texas, United States, 75093

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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