Study of Intravenous Dexamethasone in Adults Aged 58 to 85 Undergoing Total Shoulder Arthroplasty Evaluating Effects on Post-Operative Pain, Function, Nausea, Hospital Stay, and Complications

What this Trial Is About

This research aims to evaluate whether giving intravenous steroid medication during surgery can improve outcomes for patients undergoing total shoulder arthroplasty, a type of shoulder replacement surgery. The study focuses on comparing steroid supplementation to routine pain control methods to see if it reduces post-operative pain and nausea, shortens hospital stays, improves shoulder movement and function, and increases patient satisfaction. It also looks at the safety of steroid use and its effects on inflammation and long-term recovery. Participants are randomly assigned to one of two groups one receiving 9 mg of intravenous dexamethasone during surgery and the other receiving no steroid treatment. Both groups follow routine analgesia protocols otherwise. The study measures effects from the time of surgery through both short-term and long-term follow-ups, assessing pain, function, quality of life, drug use, inflammatory response, and complications. Steroid-related adverse effects and blood sugar levels are carefully monitored. During the study, participants will have their pain levels, shoulder function, satisfaction, and inflammation assessed regularly using validated clinical scores and questionnaires over periods ranging from days to several years. Hospital stay length, time to first movement and sleep, as well as the occurrence of frozen shoulder will be recorded. Safety monitoring includes tracking any adverse events related to treatment. Overall, participants may be involved for up to 10 years to evaluate both early and long-term outcomes.

Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty