Actively Recruiting

Phase 4
Age: 58Years - 85Years
All Genders
NCT04507412

Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty

Led by Christian Candrian · Updated on 2026-03-05

74

Participants Needed

1

Research Sites

624 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the study is to evaluate if intravenous steroid supplementation can provide advantages over routine analgesia protocols in terms of post-operative symptoms (pain and nausea), length of hospital stay, shoulder range of motion, function and patient satisfaction

CONDITIONS

Official Title

Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty

Who Can Participate

Age: 58Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing unilateral primary total anatomical or reverse shoulder arthroplasty (Total Shoulder Arthroplasty)
  • Patients with a BMI >18.5 and <35
  • Patients able to provide informed consent and follow all the study procedures as indicated by the protocol
  • Informed Consent as documented by signature
Not Eligible

You will not qualify if you...

  • Contraindications to steroids
  • Revision and post-traumatic TSA
  • Active steroid or immunosuppressive therapy in the last 30 days before the operation
  • Pregnant or breast-feeding women
  • Presence of other clinically significant concomitant disease states (ASA IV)
  • Uncontrolled diabetes mellitus
  • Contraindications to Non-steroidal anti-inflammatory drugs
  • Chronic systemic diseases as immunodeficiency, autoimmune disease (Systemic Lupus Erythematosus), gout, rheumatic arthritis
  • Known or suspected non-compliance, drug or alcohol abuse
  • Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant.
  • Participation in another study with investigational drug within the 30 days preceding and during the present study
  • Previous enrolment into the current study
  • Enrolment of the investigator, his/her family members, employees and other dependent persons

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Christian Candrian

Lugano, Switzerland, 6900

Actively Recruiting

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Research Team

C

Christian Candrian, Prof.Dr.med

CONTACT

G

Gyözö Lehoczky, Dr.med

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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