Actively Recruiting
Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
Led by Brigham and Women's Hospital · Updated on 2025-12-30
152
Participants Needed
1
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a randomized, double-blinded, placebo-controlled trial to compare the effectiveness of IV oxytocin infusion to placebo on peri-operative opioid consumption and reducing post-operative pain following a minimally invasive hysterectomy under general anesthesia.
CONDITIONS
Official Title
Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 18-65 years old
- ASA category 1-3
- Scheduled to undergo minimally invasive hysterectomy
- No documented allergy to oxytocin
You will not qualify if you...
- ASA category 4 or greater
- Age over 65 years old
- Additional surgical procedures such as laparotomy, omentectomy, cystectomy, vaginectomy, or endometriosis ablation
- Active opioid use exceeding 10 mg oxycodone per day
- Opioid use disorder or current treatment with naltrexone or Suboxone
- Allergies to acetaminophen, celecoxib, ketorolac, fentanyl, hydromorphone, or oxycodone
- Use of epidural or regional anesthesia for pain management
- Inability to understand questionnaires
- Surgery converted to open or extended procedure
- Intra-operative blood loss over 500 ml
- Epidural catheter placement or regional anesthesia in PACU
- Hospitalization due to surgical or anesthetic complications
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Brigham and Women's Hospital
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
J
John J. Kowalczyk, MD
CONTACT
R
Rusul I Al-Ani
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here