Actively Recruiting
Intravesical Lactobacillus for Urinary Symptoms Among People With NLUTD Who Use Indwelling Catheters
Led by Medstar Health Research Institute · Updated on 2025-10-22
182
Participants Needed
1
Research Sites
346 weeks
Total Duration
On this page
Sponsors
M
Medstar Health Research Institute
Lead Sponsor
C
Children's National Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objectives of the proposed research among this population are: 1) to define clinically meaningful change (i.e. differentiating states of health and illness) with respect to urinary symptoms, urine inflammation, cultivable bacteria, and the urine ecosystem; and 2) to determine the optimal intravesical Lactobacillus RhamnosusGG (LGG®) dose to be used to reduce urinary symptoms in a future clinical trial.
CONDITIONS
Official Title
Intravesical Lactobacillus for Urinary Symptoms Among People With NLUTD Who Use Indwelling Catheters
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Neurogenic bladder for at least 6 months
- Using indwelling catheterization for bladder management
- Women must be premenopausal and not currently menstruating
- Living in the community
- Physical disability
You will not qualify if you...
- Use of prophylactic antibiotics
- Use of intravesical antimicrobials to prevent urinary tract infection
- Psychological or psychiatric conditions affecting ability to follow instructions
- Use of oral or intravenous antibiotics within the past 2 weeks
- Sexual activity within the previous 72 hours
- Participation in another study that could affect results
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MedStar National Rehabilitation Hospital
Washington D.C., District of Columbia, United States, 20010
Actively Recruiting
Research Team
A
Amanda K Rounds, PhD
CONTACT
I
Inger H Ljungberg
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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