Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT05230511

Intravesical LGG VS Saline Bladder Wash RCT

Led by Medstar Health Research Institute · Updated on 2025-08-29

120

Participants Needed

1

Research Sites

237 weeks

Total Duration

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AI-Summary

What this Trial Is About

This is the first ever comparative effectiveness study of an antibiotic-sparing novel self-management intervention to prevent complicated urinary tract infection (UTI).

CONDITIONS

Official Title

Intravesical LGG VS Saline Bladder Wash RCT

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Spinal cord injury for at least 6 months
  • Diagnosed neurogenic lower urinary tract dysfunction
  • Using intermittent catheterization for bladder management
  • Living in the community (discharged from acute care)
Not Eligible

You will not qualify if you...

  • Known genitourinary problems beyond neuropathic bladder, such as reflux or stones
  • Use of preventative antibiotics
  • Prior use of intravesical agents like gentamycin, saline, or Lactobacillus
  • Immunodeficiency conditions
  • Oral antibiotics taken within the last 2 weeks
  • Psychological or psychiatric issues affecting ability to follow instructions
  • Participation in another conflicting clinical study
  • Exposure to intravesical LGG within the past 6 months
  • Active cancer within 5 years or active autoimmune disorder

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

MedStar National Rehabilitation Hospital

Washington D.C., District of Columbia, United States, 20010

Actively Recruiting

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Research Team

E

Emily Leonard, PhD

CONTACT

I

Inger H Ljungberg, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

4

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