Actively Recruiting
Introduction of ACI for Cartilage Repair
Led by Centre Hospitalier Universitaire Vaudois · Updated on 2026-03-11
218
Participants Needed
1
Research Sites
678 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study was aimed to evaluate effectiveness and safety of autologous chondrocyte suspension for treatment of knee articular cartilage defects.
CONDITIONS
Official Title
Introduction of ACI for Cartilage Repair
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 15 and 50 years
- Lesions classified as ICRS Grade III or IV and smaller than 15 cm2
- Lesions that have failed prior therapy (conservative or surgical treatment for 6 months or more)
- Ability to understand and sign informed consent form
You will not qualify if you...
- Body mass index (BMI) of 35 or more
- Osteoarthritis or rheumatoid arthritis
- Diffuse lesion in the knee
- Uncorrected mal-alignment, ligament instability, or meniscal tear
- Presence of growth cartilage in participants aged 15 to 18 years
- Active smoking or drug use
- Pregnancy in women
- Positive tests for HIV-1, HIV-2, Hepatitis B or C, or syphilis
- Known allergy to porcine collagen, penicillin, or gentamicin
- Poor compliance with study procedures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Centre Hospitalier Universitaire Vaudois - CHUV
Lausanne, Canton of Vaud, Switzerland, 1011
Actively Recruiting
Research Team
R
Robin MARTIN, MD
CONTACT
V
Virginie PHILIPPE, Ph-D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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